Billings were not disclosed, but privately-owned Omni spent $2.7 million in measured media last year, according to Taylor Nelson Sofres' CMR.
Omni has 40 luxury hotels and resorts in the U.S., Canada and Mexico.
DDB will work with Omni to position the brand with business professionals. Integrated communications will include national print, direct marketing and promotional programs.
Interpublic Group of Cos.' Campbell-Mithun, San Diego, was the incumbent on the account. Omni declined to disclose the finalists in the review.